SARS-CoV-2’nin yeni bir varyant\u0131, 24 Kas\u0131m 2021 g\u00fcn\u00fc, varyant B.1.1.529 bildirildi. 26 Kas\u0131m 2021’de DS\u00d6, B.1.1.529 varyant\u0131n\u0131, DS\u00d6’n\u00fcn Vir\u00fcs Evrimi Teknik Dan\u0131\u015fma Grubu’nun (TAG-VE) tavsiyesi \u00fczerine, endi\u015fe verici bir varyant olarak, Omicron ad\u0131yla belirlemi\u015ftir. Omicron’un Delta dahil di\u011fer varyantlara k\u0131yasla daha bula\u015f\u0131c\u0131 olup olmad\u0131\u011f\u0131 hen\u00fcz belli de\u011fildir. Omicron ile enfeksiyonun di\u011fer varyantlarla k\u0131yasla daha ciddi hastal\u0131\u011fa neden olup olmad\u0131\u011f\u0131 da hen\u00fcz netle\u015fmemi\u015ftir.<\/p>\n
Vitro S.A. \u015firketi, i\u00e7inde bulundu\u011fumuz salg\u0131na kar\u015f\u0131 verilen m\u00fccadeleye yard\u0131mc\u0131 olmaya devam etmek amac\u0131yla, ayr\u0131nt\u0131l\u0131 bir in silico analizi ger\u00e7ekle\u015ftirdi ve halihaz\u0131rda d\u00fcnya \u00e7ap\u0131nda ticarile\u015ftirdi\u011fi ilgili kitlerin, Omicron varyant\u0131nda tespit edilen mutasyon setlerinden ve delesyonlardan etkilenmedi\u011fi bulundu, bunlar : SARS-CoV-2 RNA tespit Kiti (MAD-003941M); FLU-COVID RT-PCR Kiti (MAD-003942M), Solunum Flow \u00c7ip Kiti (MAD-0033939M) ve SARS-CoV-2 varyantlar\u0131 RT-PCR kiti (MAD-003947M). Bu sayede bu kitler, bu yeni varyantla enfekte olmu\u015f en son vakalar dahil olmak \u00fczere SARS-CoV-2 enfeksiyonunu tespit etmek i\u00e7in kullan\u0131lmaya devam edilebilir.<\/p>\n
The Omicron variant has the 69-70del mutation of the S gene and doesn\u00b4t have the 3675-3677del mutation of the ORF1ab gene. This pattern of mutations makes possible the identification of this variant.<\/p><\/blockquote>\n
Confirmation must then be performed by sequencing the sample. Ayr\u0131ca, SARS-CoV-2 varyant RT-PCR kiti (MAD-003947M), Omicron varyant\u0131n\u0131 tan\u0131mlayabilir. GISAID kamu veri taban\u0131ndaki dizilere kar\u015f\u0131 ayr\u0131nt\u0131l\u0131 bir in silico analizi yap\u0131larak, kitimizin bu yeni varyant\u0131 do\u011fru \u015fekilde tan\u0131mlayabildi\u011fi do\u011fruland\u0131.<\/p>\n
Omicron varyant\u0131, S geninin 69-70del mutasyonuna sahip olup, ORF1ab geninin 3675-3677del mutasyonuna sahip de\u011fildir. Bu mutasyon kal\u0131b\u0131, bu varyant\u0131n tan\u0131mlanmas\u0131n\u0131 m\u00fcmk\u00fcn k\u0131lar. Numune sekans\u0131yla daha sonra do\u011frulama yap\u0131lmal\u0131d\u0131r.<\/p>\n
Vitro S.A., d\u00fcnya \u00e7ap\u0131nda i\u00e7inde bulundu\u011fumuz salg\u0131nla m\u00fccadeleye yard\u0131mc\u0131 olacak ara\u00e7lar geli\u015ftirmek i\u00e7in yenilik\u00e7i ve faydal\u0131 ara\u015ft\u0131rmalar \u00fczerinde \u00e7al\u0131\u015fmaya odaklanm\u0131\u015ft\u0131r.<\/p>\n","protected":false},"excerpt":{"rendered":"
Omicron ad\u0131yla belirlemi\u015ftir. Omicron’un Delta dahil di\u011fer varyantlara k\u0131yasla daha bula\u015f\u0131c\u0131 olup olmad\u0131\u011f\u0131 hen\u00fcz belli de\u011fildir. Omicron ile enfeksiyonun di\u011fer varyantlarla k\u0131yasla daha ciddi hastal\u0131\u011fa neden olup olmad\u0131\u011f\u0131 da hen\u00fcz netle\u015fmemi\u015ftir.<\/p>\n","protected":false},"author":18,"featured_media":5086,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[28],"tags":[],"_links":{"self":[{"href":"https:\/\/vitroturkey.bio\/tr\/wp-json\/wp\/v2\/posts\/4057"}],"collection":[{"href":"https:\/\/vitroturkey.bio\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vitroturkey.bio\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vitroturkey.bio\/tr\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/vitroturkey.bio\/tr\/wp-json\/wp\/v2\/comments?post=4057"}],"version-history":[{"count":1,"href":"https:\/\/vitroturkey.bio\/tr\/wp-json\/wp\/v2\/posts\/4057\/revisions"}],"predecessor-version":[{"id":5597,"href":"https:\/\/vitroturkey.bio\/tr\/wp-json\/wp\/v2\/posts\/4057\/revisions\/5597"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vitroturkey.bio\/tr\/wp-json\/wp\/v2\/media\/5086"}],"wp:attachment":[{"href":"https:\/\/vitroturkey.bio\/tr\/wp-json\/wp\/v2\/media?parent=4057"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vitroturkey.bio\/tr\/wp-json\/wp\/v2\/categories?post=4057"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vitroturkey.bio\/tr\/wp-json\/wp\/v2\/tags?post=4057"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}